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Основной контент книги Pharmacophores and Pharmacophore Searches
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Maht 397 lehekülge

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Pharmacophores and Pharmacophore Searches

autorid
Hugo Kubinyi,
gerd folkers
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Raamatut ei saa failina alla laadida, kuid seda saab lugeda meie rakenduses või veebis.

€230,33

Raamatust

This handbook is the first to address the practical aspects of this novel method. It provides a complete overview of the field and progresses from general considerations to real life scenarios in drug discovery research. Starting with an introductory historical overview, the authors move on to discuss ligand-based approaches, including 3D pharmacophores and 4D QSAR, as well as the concept and application of pseudoreceptors. The next section on structure-based approaches includes pharmcophores from ligand-protein complexes, FLIP and 3D protein-ligand binding interactions. The whole is rounded off with a complete section devoted to applications and examples, including modeling of ADME properties. With its critical evaluation of pharmacophore-based strategies, this book represents a valuable aid for project leaders and decision-makers in the pharmaceutical industry, as well as pharmacologists, and medicinal and chemists.

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Vanusepiirang:
0+
Ilmumiskuupäev Litres'is:
21 august 2019
Objętość:
397 lk
ISBN:
9783527608720
Üldsuurus:
20 МБ
Lehekülgede koguarv:
397
Õiguste omanik:
John Wiley & Sons Limited