Lugege ainult LitRes'is

Raamatut ei saa failina alla laadida, kuid seda saab lugeda meie rakenduses või veebis.

Основной контент книги Ligand-Binding Assays. Development, Validation, and Implementation in the Drug Development Arena
Tekst PDF

Maht 421 lehekülg

0+

Ligand-Binding Assays. Development, Validation, and Implementation in the Drug Development Arena

Lugege ainult LitRes'is

Raamatut ei saa failina alla laadida, kuid seda saab lugeda meie rakenduses või veebis.

€161,38

Raamatust

A consolidated and comprehensive reference on ligand-binding assays Ligand-binding assays (LBAs) stand as the cornerstone of support for definition of the pharmaco-kinetics and toxicokinetics of macromolecules, an area of burgeoning interest in the pharmaceutical industry. Yet, outside of the Crystal City Conference proceedings, little guidance has been available for LBA validation, particularly for assays used to support macromolecule drug development. Ligand-Binding Assays: Development, Validation, and Implementation in the Drug Development Arena answers that growing need, serving as a reference text discussing critical aspects of the development, validation, and implementation of ligand-binding assays in the drug development field. Ligand-Binding Assays covers essential topics related to ligand-binding assays, from pharmacokinetic studies, the development of LBAs, assay validation, statistical LBA aspects, and regulatory aspects, to software for LBAs and robotics and other emerging methodologies for LBAs. Highlights include: A general discussion of challenges and proven approaches in the development of ligand-binding assays More detailed examination of characteristics of these assays when applied to support of pharmacokinetic and toxicokinetic studies of compounds at different stages in the discovery or development timeline A concise, but detailed, discussion of validation of ligand-binding assays for macromolecules A practical approach to «fit-for-purpose» validation of assays for biomarkers, those molecules receiving increased attention as potentially demonstrating that the target chosen in discovery is being modulated by the candidate therapeutic, both in nonclinical and clinical studies Written by a team of world-recognized authorities in the field, Ligand-Binding Assays provides key information to a broad range of practitioners, both in the pharmaceutical and allied industries and in related contract research organizations and academic laboratories and, perhaps, even in the field of diagnostics and clinical chemistry.

Logi sisse, et hinnata raamatut ja jätta arvustus
Raamat «Ligand-Binding Assays. Development, Validation, and Implementation in the Drug Development Arena» — loe veebis. Jäta kommentaare ja arvustusi, hääleta lemmikute poolt.
Vanusepiirang:
0+
Ilmumiskuupäev Litres'is:
02 juuni 2018
Objętość:
421 lk
ISBN:
9780470541494
Üldsuurus:
8.7 МБ
Lehekülgede koguarv:
421
Õiguste omanik:
John Wiley & Sons Limited
Audio
Keskmine hinnang 4,9, põhineb 91 hinnangul
Tekst
Keskmine hinnang 4,9, põhineb 344 hinnangul
Audio
Keskmine hinnang 4,5, põhineb 240 hinnangul
Tekst, helivorming on saadaval
Keskmine hinnang 4,7, põhineb 542 hinnangul
Tekst
Keskmine hinnang 4,3, põhineb 290 hinnangul
Tekst, helivorming on saadaval
Keskmine hinnang 4,9, põhineb 1940 hinnangul
Tekst, helivorming on saadaval
Keskmine hinnang 4,7, põhineb 404 hinnangul